Khōst (Pashto: خوست, or Khēst خېست) is the capital city of Khost Province, Afghanistan. It is the largest city in the southeastern part of the country, and also the largest in the region of Loya Paktia. To the south and east of Khost lie Waziristan and Kurram in Pakistan. Khost is the home of Shaikh Zayed University. Khost Airport serves the city as well as the larger region surrounding the city.
On 15 August 2021, Khost was seized by Taliban fighters, becoming the twenty-eighth provincial capital to be captured by the Taliban as part of the wider 2021 Taliban offensive.