Aïn Séfra (Arabic: عين الصفراء, lit. yellow spring) is a municipality in Naâma Province, Algeria. It is the district seat of Aïn Séfra District and it has a population of 47,415, which gives it 11 seats in the PMA. Its postal code is 45200 and its municipal code is 4503. It is the second most populated municipality in the province after Mécheria.