Santa Cruz do Capibaribe is a Brazilian municipality in the State of Pernambuco. It is the third largest city in the mesoregion of Agreste of Pernambuco with a population of 109,897 inhabitants in 2020. It has 335.309 km² (208.5 square miles) of total area and it is located about 185.7 km (115.4 miles) from the capital Recife.
The city is famous for its textile industry together with Caruaru and Toritama.