Mestre (Italian pronunciation: [ˈmɛstre]) is part of a borough of the comune (municipality) of Venice, on the mainland opposite the historical island city of Venice, in the region of Veneto, Italy.
Administratively, Mestre forms (together with the nearby Carpenedo) the Municipalità di Mestre-Carpenedo, one of the six boroughs or districts of the comune. Sometimes it is considered as a frazione. With 88,552 (2019) inhabitants, Mestre is the most populated urban centre of the comune. The population of the borough of Mestre-Carpenedo is 89,373 (2010).