Izumisano (Japanese: 泉佐野市, Izumisano-shi, [izɨᵝmʲisano ɕi]) is a city located in Osaka Prefecture, Japan. As of 30 November 2021, the city had an estimated population of 98,840 in 47658 households and a population density of 1700 persons per km². The total area of the city is 56.51 square kilometres (21.82 sq mi).