Dothan ( DOH-thən) is a city in Dale, Henry, and Houston counties and the Houston county seat in the U.S. state of Alabama. It is Alabama's eighth-largest city, with a population of 71,072 at the 2020 census. It is near the state's southeastern corner, about 20 miles (32 km) west of Georgia and 16 miles (26 km) north of Florida. It is named after the biblical city where Joseph's brothers threw him into a cistern and sold him into slavery in Egypt.Dothan is the principal city of the Dothan, Alabama metropolitan area, which encompasses all of Geneva, Henry, and Houston counties; the small portion in Dale County is part of the Ozark Micropolitan Statistical Area. Together they form the Dothan-Ozark Combined Statistical Area. Coffee County and its Enterprise micropolitan area was originally combined as a statistical area with both Dothan and Ozark as well, but is now split off as its own statistical area by the US Census Bureau.