Huntington is a city in Cabell and Wayne counties in the U.S. state of West Virginia. It is the county seat of Cabell County, and the largest city in the Huntington–Ashland metropolitan area, sometimes referred to as the Tri-State Area. A historic and bustling city of commerce and heavy industry, Huntington has benefited from its location on the Ohio River at the mouth of the Guyandotte River. It is home to the Port of Huntington Tri-State, the second-busiest inland port in the United States. As of the 2020 census, its metro area is the largest in West Virginia, spanning seven counties across three states and having a population of 359,862. Huntington is the second-largest city in West Virginia, with a population of 46,842 at the 2020 census.