League City is a city in the U.S. state of Texas, in Galveston County, within the Greater Houston metropolitan area. As of the 2020 census, the city had a population of 112,129.The city of League City has a small portion north of Clear Creek within Harris County zoned for residential and commercial uses. It is home to several waterside resorts, such as South Shore Harbor Resort and Conference Center and Waterford Harbor and Yacht Club Marina, popular with residents of nearby Houston. Between 2000 and 2005, League City surpassed Galveston as Galveston County's largest city.