Denov (Uzbek: Denov, Tajik: Деҳнав, romanized: Dehnav, Persian: ده نو) is a city in Surxondaryo Region of southeast Uzbekistan, the administrative centre of Denov District. It is in the Hissar Range close to the border with Tajikistan, and is the closest major town to the Kalchayan and Dalverzin Tepe archaeological sites. Denov is believed to be the site of ancient city of Chaghaniyan.